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Skin lesion - lesions that are relatively site specific

Scalp

Common

  • Pilar cyst (syn. trichilemmal cyst)

Uncommon / rare

  • Naevus sebaceous (often present at birth / scalp, occasionally the face / smooth pink-yellow patch / become warty with age)
  • Atypical fibroxanthoma (mainly males / sun-exposed areas, especially the head and neck / can ulcerate)
  • Cylindroma (slow growing rubbery nodules)

Face

Common

  • Sebaceous gland hyperplasia (multiple / 1-3 mm / white-yellow papules)
  • Milia (multiple / small white papules)
  • Xanthalasmata (eyelids and medial canthus / yellow papules and plaques / single to several)
  • Fibrous papule of the face (nose most common site / solitary / skin-coloured papule)
  • Solitary circumscribed neuroma (most commonly seen near muco-cutaneous junctions of face / solitary / firm skin-coloured papule)

Uncommon

  • Dermoid cyst (often present at birth / head and neck)
  • Appendageal tumours  (more common on the face but can affect almost any part of the body)
  • Angiofibroma (multiple / snout area / skin-coloured papules / tuberous sclerosis)
  • Naevus of Ota (Asiatics / peri-orbital / blue-grey patch)

Ears

  • Chondrodermatitis nodularis helicis (painful papule)
  • Venous lake (blue / soft and compressible)
  • Weathering nodules (skin-coloured papules running along rim of ear)
  • Gouty tophi (small nodules / with time a white paste-like material drains) 
  • Angiolymphoid hyperplasia with eosinophilia (rare / around the ear most common site / clustered translucent papules)

Lips

  • Venous lake (blue, soft and compressible)
  • Mucocele (syn. mucous extravasation cyst; mucous retention cyst)
  • Fordyce spots (vermilion border of the lips, oral mucosa / yellow-white spots) 
  • Mucosal melanocytic macules (brown)
  • Leukoplakia (and other white patches in the mouth)

Trunk

Benign - common

  • Epidermoid 'sebaceous' cyst (trunk and face)
  • Keloid scar (smooth / firm / skin-coloured to red)
  • Halo naevus (esp. back / circular white zone surrounding a mole)
  • Atypical (dysplastic) naevus (scalp, trunk and buttocks)
  • Vascular tumours
  • Giant comedone (a large blackhead)

Benign - uncommon / rare

  • Pilomatricoma (face and trunk / stony hard / deep-seated)
  • Becker's naevus (shoulder to upper limb / large brown patch that develops course hair)
  • Juvenile xanthogranuloma (infants and young children / smooth, tan-orange dome-shaped papules and nodules)
  • Naevus of Ito (Asiatics / shoulder / blue-grey)

Malignant

  • Paget's disease of the nipple

Limbs

Common

  • Dermatofibroma (fawn with darker rim / firm / dimples when pinched)

Uncommon / rare

  • Pigmented spindle cell naevus of Reed (a dense black macule or papule)
  • Clear cell acanthoma (most common site is lower legs / firm nodule with scaly rim)
  • Rheumatoid nodules (ulnar border of forearm and knees / firm subcutaneous nodules)
  • Tuberous xanthomata (knees and elbows / firm, painless, red-yellow papules and nodules)
  • Cutaneous leiomyoma (painful lesions)
  • Desmoplastic naevus (rare / most common site is upper arms / similar appearance to a dermatofibroma)

Hands

Common

  • Ganglion (dorsal aspects of wrists most common site / soft subcutaneous swelling)
  • Myxoid cyst (syn. mucous cyst / shiny tense papule in posterior nail fold / can ouze clear fluid / grooves can develop in nail plate)
  • Pyogenic granuloma (red papule or nodule / eroded and bleeds easily)
  • Fibrous tumours (digits and nails / smooth nodule, can be hyperkeratotic)
  • Gouty tophi (small nodules / with time a white paste-like material drains)

Uncommon / rare

  • Zoonotic infections mainly affect the fingers, hands and other exposed sites, and are often tender:
    • Orf (relatively common / mainly sheep and goats / a small, firm, red or red-blue papule enlarges to form a target-like nodule with a red centre, a white middle and a red periphery)
    • Milker's nodule (relatively common / cows / small, red, flat-topped papule/s, which evolve into red-purple, firm nodules, 0.5-1.5 cm in diameter)
    • Anthrax (rare / lesions have a necrotic centre with an outer rim of small bullae and non-pitting oedema)
  • Rheumatoid nodules (dorsal aspects of hands / firm subcutaneous nodules)
  • Tendon xanthomata (slowly enlarging subcutaneous nodules related to the tendons or ligaments)
  • Palmar xanthomata (palmar creases / yellow macules and papules) 
  • Multicentric reticulohistiocytosis (rare / yellow-brown papules along sides of fingers)

Feet

Common

  • Talon noir (black patch caused by trauma / heel most common site)
  • Ganglion (dorsal aspects of feet and close to ankles / soft subcutaneous swelling)
  • Stucco keratosis (multiple / mainly lower legs and feet / <1cm / white / rough)
  • Piezogenic pedal papules (multiple skin coloured papules around heels)
  • Fibrous tumours (digits and nails / smooth nodule or fleshy with a scaly surface)

Uncommon / rare

  • Subungual exostosis (most commonly big toe / a firm nodule develops beneath the nail bed / the nodule usually grows over weeks-months, and develops a thick hyperkeratotic surface / nail plate separates from the bed)
  • Rheumatoid nodules (firm subcutaneous nodules)
  • Tendon xanthomata (slowly enlarging subcutaneous nodules related to the tendons or ligaments)
  • Carcinoma cuniculatum syn. epithelioma cuniculatum, verrucous carcinoma (fungating, wart-like mass on sole of foot)
  • Eccrine poroma and malignant eccrine poroma (sole of foot / moist, pink, elevated lesion)

Nails

  • Refer to the chapter on Nail disorders

Genitalia

  • Refer to the general dermatology table - Genital, oral and other mucosal membranes
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Lead Author - Dr Tim Cunliffe. Web Design - Mode Ten Designs.


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PCDS Latest News & Bulletins

PCDS Bulletin Summer 2017  |  06.06.2017
PCDS Bulletin Winter 2016  |  30.11.2016
PCDS Bulletin Summer 2016  |  13.06.2016