Granulosis rubra nasi

LAST UPDATED: Nov 22, 2021

Introduction

Granulosis rubra nasi is a rare condition characterised by hyperhidrosis of the nose.

This chapter is set out as follows:

Aetiology
History
Clinical findings
Images
Management

Aetiology

The cause is unknown
In some cases there is evidence of autosomal dominant transmission

History

Symptoms usually start in early childhood in patients aged 6 months to 10 years, but can arise at any age in childhood and occasionally in adults

Clinical findings

The initial presentation is excess sweating of the tip of the nose with small visible beads of sweat
With time erythema, papules, vesicles and telangiectasia may develop over the nose, cheeks, upper lip and chin

Clinical Images

Please refer to notes on image rights at bottom of the page with regards to individual image ownership.

Management

Granulosis rubra nasi usually resolves spontaneously around puberty; however, it occasionally persists indefinitely

Treatment with glycopyrronium bromide cream, a topical anti-cholinergic, can improve symptoms. Botulinum toxin injections have also been reported as effective

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Image Rights - The PCDS would like to thank Dermatoweb, DermQuest (Galderma), and others who have contributed images. All named individuals and organisations maintain copyright for the relevant images.