December 2019 | Case of the Month

History

A 23 year old man presented with a 4 year history of asymptomatic dull erythematous plaques on his left cheek and upper lip. There was no other personal or family history of skin problems. The patient was otherwise well, took no medication and had not been on any exotic holidays.


Examination

Unilateral dull erythematous plaques on his left cheek and upper lip, with some areas of fine scale on the cheek and some crusting of the lip.


Investigations

What is the differential and what investigations would you undertake?


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Diagnosis

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The differential included:

- Cutaneous lupus erythematosus, although a little unusual to be completely one-sided
- Mycobacterial infection, which can be a great mimicker
- Other granulomatous conditions, although the scale would make these less likely
- Tinea appeared unlikely

Blood tests (including HIV) were all negative and so I proceeded to do an incisional biopsy, sending half for histology and the other half for culture (in a pot without formaldehyde). Skin scrapping's were also sent for mycology.

Histology was very suggestive of cutaneous lupus erythematosus. Culture and further testing showed no evidence of mycobacterial infection. The patient was commenced on 0.1% betamethasone cream and given advice on UV-protection. At review 4 weeks later most of the inflammation had melted away.

Refer to the chapter on lupus erythematosus for more information.

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