November 2018 | Case of the Month

History

A 31 year old man was referred with a six month history of an asymptomatic rash on the right arm. He had no prior skin history and was otherwise well taking no medication. The patient worked as a teacher and enjoyed outdoor sports. 


Examination

There were multiple small scaly macules in a band-like distribution running down the right arm. Further examination of the skin, scalp, nails and oral mucosa was unremarkable. 


Investigations

What is the diagnosis?


Images

Diagnosis

RevealHide the answer

If this rash, with small scaly macules, was more generalised what would be the most likely diagnosis? The answer is psoriasis, which is the diagnosis here. The unusual feature is the distribution, which is referred to as Blaschkoid. 

Blaschko's lines (BL) represent a classic pattern of cutaneous mosaicism (two or more genetically different populations of cells existing side by side), occuring in a wide variety of congenital and acquired skin conditions. BL take on the following patterns:

  • Scalp - spiral
  • Face - vertical in the mid-face, laterally from the angles of mouth
  • Trunk - they differ from dermatomes in being more numerous and wave-like on the lateral trunk, and V-shaped in the middle of the back. Anteriorly they never cross the midline. Posteriorly the midline is often shifted from the anatomical midline
  • Arms and legs - linear or whorled (spiral), roughly parallel with long axis of the limbs

Refer to the chapter on Blaschko's lines for more information.

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