September 2015 | Case of the month - gain CPD points

History

A 21 year-old lady presented with a seven year history of a 'distressing' bumpy rash on her upper arms and thighs. The rash was asymptomatic. She had no other skin history and was otherwise well. Her mum had a similar problem.


Examination

The rash mainly affected her upper outer arms and thighs. There were large numbers of scaly, rough papules with varying degrees of perifollicular erythema.


Investigations

What is the diagnosis?


Images

Diagnosis

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The diagnosis is keratosis pilaris.

Keratosis pilaris (KP) is a very common skin condition characterised by keratinous plugging of hair follicles, with varying degree of perifollicular erythema, most commonly affecting the outer-upper arms and thighs.

KP is caused by abnormal keratinisation of the lining of the upper portion of the hair follicle, known as the follicular infundibulum - scale fills the follicle instead of exfoliating. Mild forms, appearing in childhood and adolescence, are extremely common and are best regarded as physiological 30-50% of cases have genetic origins, with an autosomal dominant inheritance.

KP is best described as a condition of childhood and adolescence, and although it often becomes more exaggerated at puberty, it frequently improves with age. However, some adults can have rather persistent KP.

Typical KP is symmetrical, most commonly affecting the outer-upper arms and thighs. It may also occur on the buttocks and cheeks, and less often on the forearms and upper back. The morphology is that of  large numbers of scaly, rough papules, which in essence is the keratinous plugging of hair follicles. There is varying degrees of perifollicular erythema.

No cure is available for KP and treatment is rarely helpful. Female patients, in particular, may wish to try facial exfoliators with a buff for their arms and legs. Emollients containing urea (eg Calmurid ® cream, Balneum ® cream) or salicylic acid may be of some use in making the skin feel a little more smooth.

For more information please refer to the related chapter on keratosis pilaris.

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