LAST UPDATED: Jan 31, 2025
https://www.pcds.org.uk/patient-info-leaflets/itch-pruritus-without-a-rash
Pruritus (itching) refers to a sensation in the skin which causes a desire to scratch. It is very common, and in many cases is caused by skin conditions such as eczema and urticaria. This leaflet refers to pruritus where there is no rash or visible skin disorder.
There are many potential causes including underlying diseases (i.e. a medical condition affecting internal organs such as the liver or kidneys) and certain medications. However, in many people no cause is found; this is called idiopathic pruritus - such a diagnosis can only be made if investigations have shown no underlying cause.
If the pruritus goes on for more than 6 weeks you must make an appointment to see a health professional as they will need to do a physical examination and arrange investigations including bloods tests and a chest x-ray to see if a cause can be found. If the pruritus is associated with night sweats and/or weight loss, then you must arrange an urgent appointment as this may suggest a more serious cause.
Your health professional may recommend an alternative cream, antihistamines, or tablets that act on the nerves relaying the sensation of itch to your brain. Steroid creams will not help if the skin is not inflamed (red and dry). This link provides information on specific treatments.
If you are prescribed sedating antihistamines (which make you feel tired) you need to be mindful that they may affect your driving / ability to work the next morning. Sedating antihistamines must not be used regularly in the long-term as there is some evidence linking them to an increased risk of dementia (memory loss).
Pruritus can have a significant psychological impact and may affect many areas of daily life including work and personal relationships. If the pruritus is affecting your mental health, you should discuss this with a health professional.
If your pruritus remains troublesome you may need to be referred to a specialist, who will generally be a Dermatologist. Treatment options include alternative topical treatments (creams, ointments, gels), or a course of light treatment (phototherapy).
The appointment may be face-to-face (the person attends the clinic), or a video call (teledermatology).
If investigations find a cause for the pruritus, treatment of this will sometimes lead to resolution of the itch. Stopping a causative drug can lead to resolution of pruritus. If a cause is not found, treatment is about managing the pruritus and keeping the itch to a minimum. In some, pruritus will persist for many years, in others it may resolve spontaneously (of its own accord).
This leaflet mentions ‘emollients’ (moisturisers). Pure petroleum emollients are flammable and should never be used near a naked flame. Non-paraffin-based emollients may also act as accelerants if they have a high oil content, so caution is advised with all topical treatments.
Your hands may be slippery after applying a greasy moisturiser, so allow time for them to soak in before driving or operating machinery.
If you, a family member, or friend have an undiagnosed skin condition; or you want to learn more about how to treat skin conditions, please view our short video on how to get the best from this website.
Disclaimer - the author PCDS cannot accept responsibility for any misleading or incorrect statements, and the management of individual patients remains the direct responsibility of the individual doctor. We do however hope that visitors to this site can contact us regarding comments that are considered misleading or incorrect so that we can continue to improve the site.
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