Basal cell carcinoma: solid (syn. nodular / cystic)

LAST UPDATED: Jun 05, 2026

Patient Information Leaflet
Link: Basal cell carcinoma

https://www.pcds.org.uk/patient-info-leaflets/basal-cell-carcinoma

Introduction

The solid basal cell carcinoma (BCC), sometimes referred to as nodular or cystic, is the most common type of basal cell carcinoma.

This chapter is set out as follows:


Aetiology

For more information refer to the related chapter Basal cell carcinoma - an overview.


Clinical findings

Distribution

  • Any site can be involved; the head and neck are the most commonly affected
  • The medial canthus and behind the ears are not uncommon sites; a thorough skin examination is required 

Morphology

  • Commonly raised; can be flat
  • Shiny / translucent, rolled edge, telangiectasia (more peripheral)
  • With time the nodule becomes more irregular and ulcerates
  • Very firm

Dermoscopic features (hover over terminologies for description)

  • Pinky white translucent or gelatinous background
     
  • Sharply focused arborising (branching) vessels (for more information on vessels refer to the chapter Vessel patterns in dermoscopy)
     
  • Ulcerations or erosions
     
  • Blue / grey clods (sometimes referred to as ovoid nests) or dots. Never a pigment network
     
  • Shiny white structures - strands (streaks) or blotches, seen primarily in the polarised mode
     
  • MAY globules - multiple aggregated yellow-white globules (clods). These differ from milia-like cysts as they are grouped and observed equally with non-polarised and polarised light (milia-like cysts are best seen with non-polarised light). MAY globules are positively associated with deeper-seated and histologically higher-grade tumour subtypes (eg micronodular), and negatively associated with superficial BCC

BCC in skin of colour

  • The diagnosis of BCC in skin of colour can be difficult due to its rarity and pigmentation
  • More than 50% of such cases are pigmented with a ‘pearly’ brown or black appearance and a rolled border
  • Nodular BCC are the predominant subtype; infiltrative BCC are uncommon
  • In a study of 66 BCC in skin phototypes IV or V the most common dermoscopic features were pigmented peripheral clods (61.7%), blue-white structureless areas (53.4%), ulceration (48.4%), and short arborising vessels (46.7%)

Clinical Images

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Management


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